Mini Review
A Systematic In Vivo Pharmacology Research to Establish Yupingfeng\'s Effective Asthma Methodology
Author(s): Santosh Mishra*
Although Yupingfeng's clinical impact on asthmatics has been established, no research has been done to substantiate its pharmacological mechanism. Hypothesis purpose to understand YPF's possible pharmacological mechanism and molecular basis for use in the treatment of asthma. Study methodology and design: Initially, a systems pharmacology-based approach was employed to systematically elucidate the mechanism of YPF in asthma by integrating pharmacokinetic screening, target prediction, network analysis, GO, and KEGG analyses. Second, using the online programme GEO2R, differentially expressed genes between asthma sufferers and healthy controls were discovered. Finally, molecular docking was carried out using the Discovery Studio 2020 Client version to find the ability of compounds to attach to targets based on systems pharmacology and DEGs data. The C57BL/6 mice that had been exp.. View More»
DOI:
10.14303/irjbcs.2023.28