Research Article
Tissue penetrability as a function of nanoparticle delivery mode
Author(s): Roxana Florentina Sufaru*, AnaMarina Radulescu, Ruxandra Vatavu, Anca Sava, Liviu Ciprian Gavril and Cosmin Popa
The study conducted at CEMEX Iasi was carried out on 2 groups of Wistar rats to which nanoparticles loaded with contrast agent were administered intraperitoneally and nasogastrically. The two modes of administration offered a comparison in terms of tissue penetrability. Histological samples were obtained from organ sections (heart, liver, kidney, gingiva, testis) and analysed using the NIKON Y-FL ECLIPSE E600 immunofluorescence microscope at the "Professor Doctor Nicolae Oblu" Emergency Clinical Hospital in Iasi. In terms of immunofluorescence our study showed a difference only in the case of sections taken from the gingiva... View More»
DOI:
10.14303/2141-9477.2023.22