Review Article
Diabetes and Metabolism: Type 2 Diabetes Mellitus
Author(s): Panayides Andreas*
One of the most prevalent metabolic disorders, Type 2 Diabetes (T2DM), is brought on by a combination of two primary factors: the inability of insulin-sensitive tissues to respond appropriately to insulin and defective insulin secretion by pancreatic cells. The molecular mechanisms involved in insulin synthesis, release, and detection are tightly regulated because insulin release and activity are necessary for glucose homeostasis. A metabolic imbalance that is the cause of the disease can result from flaws in any of the mechanisms involved in these processes. The key features of type 2 diabetes and the molecular mechanisms and pathways that are thought to play a role in insulin metabolism and lead to insulin resistance and T2DM are the subject of this review. In order to accomplish this, we present a summary of the data that has been collected thus far, with a particular emphasis on i.. View More»
DOI:
10.14303/2141-9477.2023.17