Research Article
Effects of Dietary Supplement Oyster Mushroom on Lipid Profile, Liver Function, Serum Electrolytes and Kidney Functions of Hyperlipidemic Wistar Rats
Author(s): Chibuzo Carole Nweze*, Olajide Nurudeen Rasaq, Ini Patrick Ekpe and Otito Adaeze Nweze
Mushrooms have been widely used for nutritional and medicinal purposes, but the possible regulation of serum
electrolytes concentration and amelioration of kidney functions as well as lipid profile and liver function enzymes
by oyster mushroom (Pleurotus ostreatus) has not been verified. Twenty adult male Wistar rats were used for
this study and were randomly distributed into five (1-5) groups. Hyperlipidemia was induced in groups 1-4 with
prednisolone (0.1ml/200g b.wt of rats) orally while group 5 animals served as positive control. This was done
repeatedly for 7days. Then, the rats in Group 1 and 3 received dried oyster mushroom (20g and 30g) respectively
per day and rat chow with water, Group 2 received pioglitazole, (0.1ml/200g), while Group 4 and 5 received rat
feed for 4 weeks. At the end of the experiment, blood samples and tissues were harvested for the de.. View More»
DOI:
10.14303/2250-9941.2022.26