Mini Review
Pharmacokinetics and biodistribution effects of certain fusion proteins on recombinant protein polymer and antibody
Author(s): Emily Antonio*
There is growing evidence that protein domains or inherently unstructured proteins serve crucial biological purposes. The polymer theory, which was created to forecast the general physical characteristics of polymers, can be usefully used to the analysis of these kinds of proteins. These theories "coarse-grain" the molecular information out of the models and replace it with a few of constants that define the polymer. This decrease in complexity makes it possible to study very large systems. The time scales that are available also greatly expand in the case of simulations. Here, we talk about how unstructured proteins can be categorised within a polymer framework and how polymer theory can be applied to them. In order to predict functionally significant properties like gyration radius, height of a polymer brush, and force needed to compress a polymer brush, we then review pol.. View More»
DOI:
10.14303/2250-9941.2022.43