+44 330 818 7254 Short Communication
Clinical Microbiology 2015: Chips for antimicrobial drug discovery and diagnosis- Anand Ramasubramanian- University of Texas at San Antonio
Author(s): Anand Ramasubramanian
We have an interest within the development of microscale technologies for applications in drug development and diagnostics for infectious diseases. We’ve developed a high-density microarray platform (‘chips’) consisting of nano-liter volumes of microbial pathogens on chemically modified glass slides employing a robotic microarray. We’ve successfully grown 1200 individual cultures of 30 n-L volume on a typical glass slide consisting of either single or polymicrobial cultures of Candida albicans, Pseudomonas aeruginosa or Staphylococcus aureus as biofilms. These nano bio-films display morphological complexity, three dimensional architecture an.. View More»