+44 330 818 7254Parameswari E., Udayasoorian C., S. Paul Sebastian and R.M. Jayabalakrishnan
Nanotechnology is expected to open new avenues to fight and prevent disease using atomic scale tailoring of materials. Among the most promising nanomaterials with antibacterial properties are metallic nanoparticles, which exhibit increased chemical activity due to their large surface to volume ratios and crystallographic surface structure. In this work we conducted batch experiments to assess the efficiency of silver nanoparticles synthesized by citrate reduction method for their antimicrobial property. The antimicrobial activity of silver nanoparticles and AgNO3 was compared in terms of Escherichia coli growth rate, zone of inhibition and time dependent antimicrobial activity. Silver nanoparticles showed 100 per cent growth reduction of E. coli when treated with 30 µg ml–1 concentrations, whereas the effect was much less at this concentration of AgNO3. Zone of inhibition test was also done for identification of degree of inhibition by using different concentration of AgNO3 and silver nanoparticles. It was found that, 10 µg ml-1 concentration was able to inhibit bacterial growth and created a zone of 0.8 cm by AgNO3 and 1.7 cm by Ag nanoparticles. Thus Ag nanoparticles are found to be efficient candidate for antimicrobial activity than AgNO3.
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