Adejumobi A.E, Areola J.O and Babalola O.O.
his study was carried out to investigate the possibl e hepatoprotective potentials of methanolic leaf extract of Jatropha curcas Linn on cadmium induced hepatotoxicity and oxidative stress in rabbits. Sixteen matured rabbits were used for the study; they were divided into four groups and treated as follows: Group I (control) was treated with normal saline (0.85% w/v NaCl) at 2 ml/kg body weight per day. Group II were treated with only cadmium chloride at 1.25 mg/kg body weight per day. Groups III and IV were pre-treated with 300 mg/kg body weight per day of Jatropha curcas extract and vitamin E respectively, one hour later, cadmium chloride was administered to them at 1.25 mg/kg body weight. All the animals were treated orally for 10 days.
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