+44 330 818 7254Ejele A.E., Nweze A.C. and Alinnor J.I.
The antimicrobial screening of two crude phenolic isolates from Garcinia kola (bitter kola) extract has been reviewed. The results showed that both isolates possessed antimicrobial activity to various extents and inhibited the growth of several human pathogens, which include Candida albicans, Coliform bacilli, E. coli, Pseudomonasia spp., Salmonella typhi, Staphylococcus aureus and Streptococcus spp. with inhibition zone diameters ranging between 10 and 30 mm. The results showed that the isolate of basic metabolite (Tannin–1) exhibited greater antimicrobial activity than that of acidic metabolite (Flavonoid-1). The highest antimicrobial activity was shown by Tannin–1 against Streptococcus spp., Coliform bacilli, and Salmonella typhi with inhibition zone diameter of 30mm while the smallest antimicrobial activity was shown by Flavonoid–1 against Staphylococcus aureus and Streptococcus spp. with inhibition zone diameter of 10mm. It was concluded that Garcinia kola could be the source of effective antimicrobial drugs for use in the treatment of several human pathogens.
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