Okondza Nohya Delvina*, Soudy Imar Djibrine, Amine Alhadj Souleymane, Patcha Madjimbaye, Mahamat Djidda Adoum, Abdelkarim Hamit Daoud and Lenga Arsene
Introduction: Diabetes is a serious chronic disease that occurs when the pancreas does not produce enough insulin or when the body does not properly use the insulin produced. A distinction is made between type 1 and type 2 diabetes, which increases the risk of death. This work aims to study the anti-hyperglycemic effect of B. senegalensis used in Chad to fight type II diabetes and metabolic syndrome.
Methodology: The Oral Glucose Tolerance Test was carried out, causing hyperglycemia in rabbits, followed by the incorporation of aqueous extract of Boscia senegalensis in the treatment batch. Then, a toxicity study was carried out using a standard method.
Results: The results showed that in treated rabbits, the incorporation of aqueous extract of B. senegalensis after glucose administration, led to a drop in blood sugar (1.35 mg/dl to 1.22 mg/dl). The increase in blood glucose in control rabbits (1.23 mg/dl to 1.38 mg/dl) due to glucose administration persisted. The ratio of organ weight and body weight of the two lots of rabbits showed no significant difference.
Conclusion: This study confirmed the safety of B. senegalensis extract and reduce significantly the rate of glucose in the blood fighting against type 2 diabetes.
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