+44 330 818 7254Escherichia coli isolates from domestic animals in Osun State, Nigeria, including cows, goats, and chickens, that appeared to be in good health were used in this investigation to assess the profile of antibiotic resistance. Eosin methylene Blue Agar (EMB) was used to isolate E. coli, which was then identified using standard microbiological methods. Using the disc diffusion technique, the isolate was screened against 14 antibiotics. Each isolate shown resistance to at least four out of the eight tested antibiotics, making a total of 42 distinct antibiotic resistance profiles visible. Generally speaking, the E. coli isolates showed resistance to Ampicilin at a rate of 93.8 percent; Chloramphenicol at 15.3 percent; Cloxacillin at 52.7 percent; Erythromycin at 74.3 percent; Gentamicin at 20.9 percent; Penicillin at 53.8 percent; Streptomycin at 17.7 percent; Tetracyclin at 67.3 percent; and Ceftazidine at 21.1 percent. 70.7 % to cefuroxine, 20.5 % to cefixine, 28.8 % to ofloxacine, and 58.6 % to Ciprofloxacin. According to statistical research, cows had a substantially greater average number of resistance phenotypes per isolate than did poultry (Behr H et al., 1994). The fact that multi-drug resistant commensal E. coli strains may operate as a possible gene reservoir for resistance that might spread to dangerous bacteria raises serious concerns for public health, according to this study
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