International Research Journal of Biochemistry and Bioinformatics (ISSN-2250-9941) Vol. 7(1) pp.012-018, March, 2017. DOI: http:/dx.doi.org/10.14303/irjbb.2017.011. Copyright © 2017 International Research Journals  

 

Full Length Research Paper

Prevalence and factors associated with dyslipidemia among menopausal women in the city of Parakou (Benin)

Moutawakilou Gomina1,5*, Ruth N. Mfoumou Ele1, Rachidi Sidi Imorou2, Adébayo Alassani3, Gilbert Djidonou4, Haziz Sina5, Lamine Baba-Moussa5, Simon Akpona1 

1Unit of Teaching and Research in Biochemistry, Faculty of Medicine, University of   Parakou, PO Box 123 Parakou (Republic of Benin)

2Unit of Teaching and Research in Gynecology and Obstetrics, Faculty of Medicine, University of Parakou, PO Box 123 Parakou (Republic of Benin)

3Unit of Internal Medicine, CHUD-B/A, PO Box 02 Parakou (Republic of Benin)

4Biochemistry Laboratory, CHUD-B/A, PO Box 02 Parakou (Republic of Benin)

5Laboratory of Biology and Molecular Typing in Microbiology, Department of Biochemistry and Cell Biology, Faculty of Sciences and Techniques, University of Abomey-Calavi, 05 BP 1604 Cotonou (Republic of Benin)

*Corresponding author: E-mail: elboutraguero@yahoo.fr; Tel: +229 95 96 69 40

Abstract               

 

Cases of dyslipidemia associated with menopause increase risk for cardiovascular diseases during that period of life. The purpose of this study was to determine the prevalence and factors associated with dyslipidemia among menopausal women in the city of Parakou. It was a cross-sectional study with descriptive and analytical purpose, which had been carried out from 20 February to 20 May, 2016 in Parakou (Benin). Lipid parameters were measured in 379 menopausal women. The criteria of the National Cholesterol Education Program Adult Treatment Panel III were used to identify dyslipidemia cases. The overall prevalence of dyslipidemia was estimated at 86.98%. The different types of dyslipidemia which were identified were: hypercholesterolemia (53.03%), LDL hypercholesterolemia (47.72%), hypertriglyceridemia (29.02%), HDL hypocholesterolemia (25.33%), mixed hyperlipidemia (17.94%) and atherogenic dyslipidemia (2.34%). Abdominal obesity (p=0.03) was significantly associated with hypercholesterolemia. Alcohol excessive drinking was significantly associated with HDL hypocholesterolemia (p=0.00). Obesity (p=0.03) and history of diabetes mellitus (p=0.00) were significantly associated with hypertriglyceridemia. Obesity (p=0.02) was significantly associated with mixed hyperlipidemia. Prevalence of dyslipidemia in the menopausal women of Parakou is high. Preventive measures must be implemented in order to reduce those abnormal lipid parameters. 

 

Keywords: Dyslipidemia, menopause, cholesterol, associated factors, Benin